Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16710547 | 0.91 | MAOB (0.71) | MAOBRAB9ANPC1BCHEAPP | |
| SCHEMBL2094987 | 0.88 | MAOB (0.71) | MAOBBCHE | |
| SCHEMBL13462938 | 0.87 | MAOB (0.65) | MAOBRAB9ANPC1TDP1BCHE | |
| SCHEMBL14547318 | 0.86 | MAOB (0.81) | MAOBRAB9ANPC1BCHEABCB1 | |
| SCHEMBL16710633 | 0.85 | MAOB (0.71) | MAOBRAB9ATDP1PKMSMN1; SMN2 | |
| SCHEMBL10819596 | 0.84 | MAOB (0.60) | MAOBRAB9ANPC1TDP1BCHE | |
| SCHEMBL31264 | 0.84 | IDO1 (0.71) | MAOBABCB1 | |
| SCHEMBL19684429 | 0.83 | TDP1 (0.50) | MAOBRAB9ANPC1TDP1ABCB1 | |
| SCHEMBL24041859 | 0.83 | CYP4F2 (0.74) | MAOBRAB9ANPC1TDP1BCHE | |
| SCHEMBL10819608 | 0.83 | NPC1 (0.61) | MAOBRAB9ANPC1TDP1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222381-B2 | Derivatives of monosaccharides for drug discovery | ALCHEMIA LIMITED (AU) | 2012-07-17 | — | — | US | disclosed |