SCHEMBL31264

SCHEMBL31264

COCc1cccc(OC)c1

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.71
AGXT P21549 2/20 0.71
MAOB P27338 7/20 0.61
TAAR1 Q96RJ0 3/20 0.60
CHRM2 P08172 1/20 0.56
CHRM1 P11229 1/20 0.56
CHRM3 P20309 1/20 0.56
CMA1 P23946 1/20 0.55
ABCB1 P08183 1/20 0.54
HTR1A P08908 1/20 0.54
DRD2 P14416 1/20 0.54
SIGMAR1 Q99720 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16710547 0.92 MAOB (0.71) IDO1AGXTMAOBABCB1HTR1A
SCHEMBL11590273 0.89 IDO1 (0.59) IDO1AGXTMAOBTAAR1CHRM2
SCHEMBL3768643 0.87 IDO1 (0.71) IDO1AGXTMAOBTAAR1CHRM2
SCHEMBL20795337 0.87 IDO1 (0.55) IDO1AGXTMAOBTAAR1
SCHEMBL10820376 0.84 MAOB (0.67) MAOBABCB1
SCHEMBL487468 0.84 IDO1 (0.48) IDO1AGXTMAOB
SCHEMBL8583458 0.83 IDO1 (0.53) IDO1AGXTMAOBTAAR1CHRM2
SCHEMBL1144902 0.83 IDO1 (0.67) IDO1AGXTMAOBTAAR1CHRM2
SCHEMBL27886344 0.83 IDO1 (0.67) IDO1AGXTMAOBTAAR1CHRM2
SCHEMBL3389080 0.83 IDO1 (0.67) IDO1AGXTMAOBTAAR1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118164991-A Preparation method of aminopyrimidino pyrazole/pyrrole derivative 四川大学华西医院 2024-06-11 CN claimed
CN-117886540-A Preparation method of concrete segregation-resistant agent and segregation-resistant agent 四川庄大混凝土有限公司 2024-04-16 CN claimed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
CN-100503798-C Household product TAKASAGO PERFUMERY CO LTD (JP) 2009-06-24 CN claimed
CN-1730637-A Household product TAKASAGO PERFUMERY CO LTD (JP) 2006-02-08 CN claimed
CN-118164991-A Preparation method of aminopyrimidino pyrazole/pyrrole derivative 四川大学华西医院 2024-06-11 CN disclosed
CN-114763312-B Method for inducing H halogenation in C-H on benzene ring or heterocycle through ultraviolet light 中国科学院大连化学物理研究所 2024-06-07 CN disclosed
US-11998538-B2 Piperidine urea derivatives as soluble epoxide hydrolase inhibitors NEUROPN THERAPEUTICS (US) 2024-06-04 US disclosed
CN-117886540-A Preparation method of concrete segregation-resistant agent and segregation-resistant agent 四川庄大混凝土有限公司 2024-04-16 CN disclosed
CN-117886540-A Preparation method of concrete segregation-resistant agent and segregation-resistant agent 四川庄大混凝土有限公司 2024-04-16 CN disclosed
CN-112912390-B GLP-1 analogues and methods of preparation 北京费森尤斯卡比医药有限公司 2023-12-15 CN disclosed
CN-117098670-A Thermosensitive recording medium 日本制纸株式会社 2023-11-21 CN disclosed
WO-2004108661-A1 AMIDINO COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS AXYS PHARMACEUTICALS (US) 2004-12-16 WO disclosed
EP-1475374-A1 THIADIAZOLE COMPOUNDS AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-10 EP disclosed
EP-1277741-A1 CYCLIC COMPOUNDS TANABE SEIYAKU CO., LTD. (JP) 2003-01-22 EP disclosed
US-4195178-A Methylenecyclopentane derivatives THE UPJOHN COMPANY (US) 1980-03-25 US disclosed
US-4181798-A Methylenecyclopentane derivatives THE UPJOHN COMPANY (US) 1980-01-01 US disclosed
US-4175202-A 4,5,6-Trinor-3,7,-inter-m-phenylene prostaglandin A1 analogs THE UPJOHN COMPANY (US) 1979-11-20 US disclosed
US-4100192-A Inter-phenylene-PG amides THE UPJOHN COMPANY (US) 1978-07-11 US disclosed
US-4084058-A HYPOTENSIVES, ANTICOAGULANTS THE UPJOHN COMPANY (US) 1978-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11998538-B2 Piperidine urea derivatives as soluble epoxide hydrolase inhibitors EPHX1, EPHX2, HPGDS IDO1 2233/4885AGXT 3226/4885MAOB 2529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.