Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA6 | P23280 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10820627 | 0.90 | PAOX (0.52) | FAAHCA12CA6CA7CA9 | |
| SCHEMBL13755980 | 0.89 | FAAH (0.52) | FAAHALDH1A1MEN1KMT2APAOX | |
| SCHEMBL10820630 | 0.89 | FAAH (0.52) | FAAHALDH1A1MEN1KMT2APAOX | |
| SCHEMBL10820621 | 0.85 | FAAH (0.54) | FAAHCA12CA6CA7CA9 | |
| SCHEMBL13756030 | 0.85 | FAAH (0.40) | FAAHPAOXEPHX2CASP2SLC6A5 | |
| Methyl Alcohol SCHEMBL28190236 | 0.83 | CA12 (0.43) | CA12CA6CA7CA9CA14 | |
| SCHEMBL15963174 | 0.83 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL20362854 | 0.82 | CASP2 (0.39) | FAAHALDH1A1MEN1KMT2APAOX | |
| SCHEMBL23733193 | 0.81 | FAAH (0.48) | FAAHALDH1A1MEN1KMT2ACASP2 | |
| SCHEMBL17624947 | 0.81 | FAAH (0.52) | FAAHALDH1A1MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2476756-A1 | Amine-containing lipids and uses thereof | Massachusetts Institute of Technology (US) | 2012-07-18 | — | — | EP | disclosed |
| WO-2009097332-A2 | THERAPEUTIC COMPOSITIONS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2009-08-06 | — | — | WO | disclosed |