Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13755980 | 0.90 | FAAH (0.52) | FAAHMCL1CASP2EPHX2KMT2A | |
| SCHEMBL10820630 | 0.90 | FAAH (0.52) | FAAHMCL1CASP2EPHX2KMT2A | |
| SCHEMBL10820621 | 0.86 | FAAH (0.54) | FAAHMCL1CASP2EPHX2KMT2A | |
| SCHEMBL6732754 | 0.86 | MCL1 (0.52) | FAAHMCL1CASP2KMT2AMEN1 | |
| SCHEMBL21658310 | 0.84 | FAAH (0.47) | FAAHMCL1EPHX2KMT2AMEN1 | |
| SCHEMBL8956531 | 0.82 | HDAC3 (0.43) | FAAHMCL1CASP2KMT2AMEN1 | |
| SCHEMBL20362854 | 0.82 | CASP2 (0.39) | FAAHMCL1CASP2KMT2AMEN1 | |
| SCHEMBL5909462 | 0.81 | FAAH (0.64) | FAAHMCL1CASP2KMT2AMEN1 | |
| SCHEMBL6733595 | 0.81 | MCL1 (0.47) | FAAHMCL1CASP2KMT2AMEN1 | |
| SCHEMBL10820649 | 0.81 | FAAH (0.48) | FAAHMCL1CASP2EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044585-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |