Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22370925 | 0.81 | MEN1 (0.48) | MEN1KMT2ALMNAALDH1A1ATM | |
| SCHEMBL14910876 | 0.76 | MEN1 (0.43) | MEN1KMT2ALMNAALDH1A1ATM | |
| SCHEMBL531534 | 0.69 | MEN1 (0.37) | MEN1KMT2ALMNAALDH1A1ATM | |
| SCHEMBL19354535 | 0.66 | IDO1 (0.43) | KDM4EL3MBTL1 | |
| SCHEMBL19354261 | 0.66 | IDO1 (0.43) | KDM4EL3MBTL1 | |
| SCHEMBL11326774 | 0.66 | ALDH1A1 (0.38) | KMT2AALDH1A1KDM4EATMPOLB | |
| SCHEMBL11528941 | 0.66 | CYP1A2 (0.42) | — | |
| SCHEMBL2093344 | 0.65 | CYP1A2 (0.39) | — | |
| SCHEMBL11568927 | 0.65 | TDP1 (0.55) | MEN1KMT2ALMNAALDH1A1ATM | |
| SCHEMBL5908164 | 0.65 | CYP1A2 (0.45) | ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604386-A | CONTROL OF GRAMPOSITIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0168222-A2 | 3-(Alkynylalkyloxy) Cephalosporins | ELI LILLY AND COMPANY (US) | 1986-01-15 | — | — | EP | disclosed |