Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30588975 | 1.00 | IDO1 (0.55) | IDO1MEN1KMT2AATMMTNR1A | |
| SCHEMBL6380847 | 0.79 | IDO1 (0.54) | IDO1MEN1KMT2AATMMTNR1A | |
| SCHEMBL30023288 | 0.75 | GAA (0.57) | IDO1MEN1KMT2AKDM1AALDH1A1 | |
| SCHEMBL11652329 | 0.75 | GAA (0.57) | IDO1MEN1KMT2AKDM1AALDH1A1 | |
| SCHEMBL10656824 | 0.75 | GSK3B (0.51) | MEN1KMT2AATMALDH1A1MAPT | |
| SCHEMBL10575685 | 0.75 | GSK3B (0.51) | MEN1KMT2AATMALDH1A1MAPT | |
| SCHEMBL8922115 | 0.75 | GSK3B (0.51) | MEN1KMT2AATMALDH1A1MAPT | |
| SCHEMBL11645287 | 0.75 | TDP1 (0.44) | IDO1ALDH1A1MAPTHTTTDP1 | |
| SCHEMBL6277589 | 0.75 | TDP1 (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL11566163 | 0.75 | TDP1 (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61025491-A | — | — | None | — | — | JP | disclosed |
| US-20230272401-A1 | COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF | Genetic Intelligence, Inc | 2023-08-31 | — | — | US | disclosed |
| WO-2016044777-A1 | HAT INHIBITORS AND METHODS FOR THEIR USE | ABBVIE INC. (US) | 2016-03-24 | — | — | WO | disclosed |
| JP-S6125491-A | N-CARBAMOYL-D-NAPHTHYLGLYCINE AND ITS PREPARATION | KANEGAFUCHI CHEM IND CO LTD | 1986-02-04 | — | — | JP | disclosed |
| JP-S06125491-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230272401-A1 | COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF | TARDBP, FUS, RBM17 | IDO1 4873/4885MEN1 4364/4885KMT2A 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.