Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822413 | 1.00 | CA1 (0.49) | CA1CA2TSHRRAB9ANPC1 | |
| SCHEMBL9812035 | 0.78 | GAA (0.55) | TSHRRAB9AMAPTGAAKMT2A | |
| SCHEMBL9811881 | 0.78 | GAA (0.55) | TSHRRAB9AMAPTGAAKMT2A | |
| SCHEMBL9812040 | 0.78 | CA1 (0.51) | CA1CA2TSHRRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL9812039 | 0.78 | GAA (0.54) | TSHRRAB9AMAPTGAAKMT2A | |
| SCHEMBL10808764 | 0.77 | ADRB1 (0.49) | CA1CA2TSHRLOXL2L3MBTL1 | |
| SCHEMBL1428309 | 0.77 | CA1 (0.56) | CA1CA2TSHRRAB9ANPC1 | |
| Toluene SCHEMBL10507285 | 0.76 | TDP1 (0.54) | CA1CA2TSHRRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL10508096 | 0.76 | ADRB1 (0.48) | CA1CA2TSHRLOXL2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL10818347 | 0.76 | ADRB1 (0.48) | CA1CA2TSHRLOXL2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585796-A | HYPOGLYCEMIC, ANTI-OBESITY | HOFFMANN-LA ROCHE INC. (US) | 1986-04-29 | — | — | US | disclosed |