Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11233875 | 0.83 | SIGMAR1 (0.63) | CA1CA2RAB9ANPC1TSHR | |
| Hydrochloric Acid SCHEMBL11179406 | 0.83 | SIGMAR1 (0.63) | CA1CA2RAB9ANPC1TSHR | |
| SCHEMBL8882205 | 0.83 | SIGMAR1 (0.66) | CA1CA2RAB9ANPC1TSHR | |
| SCHEMBL2990495 | 0.83 | CA1 (0.58) | CA1CA2RAB9ANPC1TSHR | |
| SCHEMBL10822395 | 0.82 | MGLL (0.50) | CA1CA2RAB9ANPC1TSHR | |
| SCHEMBL10822396 | 0.82 | MGLL (0.50) | CA1CA2RAB9ANPC1TSHR | |
| SCHEMBL10508374 | 0.80 | ADRB3 (0.77) | ADRB1ADRB3CASP3 | |
| SCHEMBL11174788 | 0.80 | ADRB3 (0.77) | ADRB1ADRB3CASP3 | |
| SCHEMBL9006725 | 0.80 | ADRB3 (0.77) | ADRB1ADRB3CASP3 | |
| SCHEMBL7153662 | 0.80 | ADRB3 (0.77) | ADRB1ADRB3CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170121-B1 | 2-HYDROXY-3-ARYLOXYPROPYL OR 2-HYDROXY-2-BENZOFURANYL ETHYL TERTIARY AMINE HAVING AN ANTI-HYPERGLYCAEMIC AND/OR ANTI-OBESITY ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-06-19 | — | — | EP | disclosed |
| EP-0170121-A1 | 2-Hydroxy-3-aryloxypropyl or 2-hydroxy-2-benzofuranyl ethyl tertiary amine having an anti-hyperglycaemic and/or anti-obesity activity | BEECHAM GROUP PLC (GB) | 1986-02-05 | — | — | EP | disclosed |