Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822717 | 0.92 | MAPT (0.59) | MAPTSMN1; SMN2TSHRPOLBKDM4E | |
| SCHEMBL10822388 | 0.87 | MAPT (0.53) | MAPTSMN1; SMN2TSHRPOLBKDM4E | |
| SCHEMBL10483367 | 0.85 | NPC1 (0.51) | SMN1; SMN2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL10483366 | 0.85 | NPC1 (0.51) | MAPTSMN1; SMN2POLBKDM4EALDH1A1 | |
| SCHEMBL10483431 | 0.85 | NPC1 (0.51) | MAPTSMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL9566519 | 0.84 | AAK1 (0.55) | MAPTSMN1; SMN2TSHRPOLBKDM4E | |
| SCHEMBL10483348 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL10483542 | 0.81 | ALDH1A1 (0.51) | SMN1; SMN2KDM4EALDH1A1LMNANPC1 | |
| SCHEMBL10822854 | 0.80 | TSHR (0.54) | MAPTSMN1; SMN2TSHRPOLBKDM4E | |
| SCHEMBL9566451 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593025-A | A 2-naphthyl-4,6-diamino-s-triazine compound | NIPPON SHINYAKU CO., LTD. (JP) | 1986-06-03 | — | — | US | claimed |
| US-4554275-A | Triazine derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 1985-11-19 | — | — | US | claimed |
| US-4593025-A | A 2-naphthyl-4,6-diamino-s-triazine compound | NIPPON SHINYAKU CO., LTD. (JP) | 1986-06-03 | — | — | US | disclosed |
| US-4554275-A | Triazine derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 1985-11-19 | — | — | US | disclosed |