Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483348 | 0.88 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1MEN1KMT2ALMNA | |
| SCHEMBL9566519 | 0.88 | AAK1 (0.55) | TSHRSMN1; SMN2POLBMAPTNPC1 | |
| SCHEMBL10822516 | 0.85 | RAB9A (0.58) | SMN1; SMN2MAPTNPC1MEN1KMT2A | |
| SCHEMBL9566608 | 0.81 | NPC1 (0.58) | SMN1; SMN2NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL10822653 | 0.80 | MAPT (0.54) | TSHRSMN1; SMN2POLBSCDMAPT | |
| SCHEMBL8413034 | 0.80 | HDAC1 (0.56) | TSHRSMN1; SMN2POLBNPC1MEN1 | |
| SCHEMBL9566506 | 0.79 | HDAC1 (0.60) | SMN1; SMN2POLBNPC1CYP11B2CYP11B1 | |
| SCHEMBL9566457 | 0.79 | SMN1; SMN2 (0.55) | TSHRSMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL9566631 | 0.79 | MEN1 (0.56) | TSHRSMN1; SMN2POLBNPC1MEN1 | |
| SCHEMBL11591085 | 0.78 | HDAC1 (0.60) | SMN1; SMN2NPC1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593025-A | A 2-naphthyl-4,6-diamino-s-triazine compound | NIPPON SHINYAKU CO., LTD. (JP) | 1986-06-03 | — | — | US | claimed |
| US-4554275-A | Triazine derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 1985-11-19 | — | — | US | claimed |
| US-4593025-A | A 2-naphthyl-4,6-diamino-s-triazine compound | NIPPON SHINYAKU CO., LTD. (JP) | 1986-06-03 | — | — | US | disclosed |
| US-4554275-A | Triazine derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 1985-11-19 | — | — | US | disclosed |