Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822854 | 0.88 | TSHR (0.54) | AAK1LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL10822653 | 0.84 | MAPT (0.54) | LMNAMAPK1KDM4EMAPTALDH1A1 | |
| SCHEMBL10483348 | 0.84 | SMN1; SMN2 (0.59) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10822388 | 0.83 | MAPT (0.53) | LMNAMAPK1KDM4EMAPTALDH1A1 | |
| SCHEMBL9566608 | 0.83 | NPC1 (0.58) | ALDH1A1SMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL8413034 | 0.82 | HDAC1 (0.56) | LMNAKDM4EALDH1A1GAATSHR | |
| SCHEMBL9566506 | 0.81 | HDAC1 (0.60) | AAK1LMNAMAPK1GAASMN1; SMN2 | |
| SCHEMBL9566457 | 0.81 | SMN1; SMN2 (0.55) | LMNAMAPK1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL9566631 | 0.81 | MEN1 (0.56) | LMNAMAPK1KDM4EGAATSHR | |
| SCHEMBL11591466 | 0.80 | HDAC1 (0.60) | LMNAALDH1A1SMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |