Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823664 | 0.87 | PTGES (0.47) | HSD17B1HSD17B2PTGESMEN1KMT2A | |
| SCHEMBL10823355 | 0.86 | IDH1 (0.48) | IDH1PKMHSD17B1HSD17B2MEN1 | |
| SCHEMBL10823596 | 0.85 | TRPV1 (0.51) | TRPV1MEN1KMT2ALMNAMAPT | |
| SCHEMBL10823363 | 0.82 | IDH1 (0.58) | IDH1 | |
| SCHEMBL10823613 | 0.82 | PRMT1 (0.49) | IDH1PKM | |
| SCHEMBL10823553 | 0.81 | PTGES (0.50) | IDH1PKMTRPV1PTGESMEN1 | |
| SCHEMBL10823421 | 0.81 | MEN1 (0.48) | IDH1PKMTRPV1MEN1KMT2A | |
| SCHEMBL10823404 | 0.81 | MEN1 (0.48) | IDH1PKMTRPV1MEN1KMT2A | |
| SCHEMBL10823575 | 0.81 | MEN1 (0.48) | IDH1PKMTRPV1MEN1KMT2A | |
| SCHEMBL11341898 | 0.81 | TRPV1 (0.52) | PKMTRPV1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |