Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823374 | 0.87 | IDH1 (0.48) | PTGESLMNAHSD17B1HSD17B2MEN1 | |
| SCHEMBL10823714 | 0.86 | LMNA (0.45) | DYRK1ALMNAPOLBGAAGFER | |
| SCHEMBL10823363 | 0.85 | IDH1 (0.58) | — | |
| SCHEMBL10823553 | 0.84 | PTGES (0.50) | PTGESGAAMEN1ALDH1A1KMT2A | |
| SCHEMBL11343949 | 0.81 | ENPP2 (0.56) | DYRK1APRMT1 | |
| SCHEMBL10823632 | 0.81 | PRMT1 (0.60) | LMNAPRMT1 | |
| SCHEMBL10823696 | 0.80 | TIMP3 (0.47) | DYRK1ALMNAPOLBGAAGFER | |
| SCHEMBL10823568 | 0.80 | LMNA (0.44) | DYRK1ALMNAPOLBGAAGFER | |
| SCHEMBL10823386 | 0.80 | TIMP3 (0.47) | DYRK1ALMNAPOLBGAAGFER | |
| SCHEMBL10823450 | 0.79 | CA2 (0.49) | LMNASMN1; SMN2PRMT1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |