Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823499 | 0.88 | KMT2A (0.42) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL10823417 | 0.86 | EP300 (0.46) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL10823487 | 0.85 | EP300 (0.46) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL10823460 | 0.84 | CA12 (0.43) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL10823689 | 0.84 | MEN1 (0.46) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL10823453 | 0.84 | LMNA (0.46) | CA2MEN1KMT2AHKDC1HCRTR1 | |
| SCHEMBL10823595 | 0.83 | UQCRB (0.41) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL10823534 | 0.83 | CA12 (0.45) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL11341085 | 0.83 | HPSE (0.43) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL10823390 | 0.82 | HKDC1 (0.46) | CA12CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |