Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823564 | 0.91 | MAPT (0.53) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823717 | 0.90 | MEN1 (0.49) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823663 | 0.88 | LMNA (0.47) | MEN1KMT2ALMNAHTT | |
| SCHEMBL10823435 | 0.85 | KMT2A (0.52) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823670 | 0.85 | KMT2A (0.52) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823480 | 0.84 | MAPT (0.50) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823457 | 0.82 | IDH1 (0.56) | IDH1 | |
| SCHEMBL10823633 | 0.82 | CA12 (0.42) | MEN1KMT2ALMNAHTTCA12 | |
| SCHEMBL10823442 | 0.81 | MEN1 (0.49) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823548 | 0.81 | MEN1 (0.49) | MEN1KMT2AMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |