Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823344 | 0.90 | EP300 (0.50) | LMNAMEN1HTTKMT2AEP300 | |
| SCHEMBL10823540 | 0.88 | MEN1 (0.53) | LMNAMEN1HTTKMT2A | |
| SCHEMBL10823431 | 0.87 | CHEK1 (0.45) | LMNAMEN1HTTKMT2ABDKRB1 | |
| SCHEMBL10823633 | 0.84 | CA12 (0.42) | LMNAMEN1HTTKMT2AEP300 | |
| SCHEMBL10823457 | 0.84 | IDH1 (0.56) | — | |
| SCHEMBL10823707 | 0.83 | MEN1 (0.49) | LMNAMEN1HTTKMT2ABDKRB1 | |
| SCHEMBL10823378 | 0.83 | MEN1 (0.49) | LMNAMEN1HTTKMT2ABDKRB1 | |
| SCHEMBL10823559 | 0.83 | LMNA (0.50) | LMNAMEN1KMT2AGAAGHSR | |
| SCHEMBL10823732 | 0.82 | KMT2A (0.50) | LMNAMEN1HTTKMT2ABDKRB1 | |
| SCHEMBL11355263 | 0.81 | TIMP3 (0.54) | MEN1KMT2AEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |