Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HK1 | P19367 | 2/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823573 | 0.91 | MCL1 (0.45) | EP300KAT2BKAT8KEAP1NFE2L2 | |
| SCHEMBL10823622 | 0.90 | HPSE (0.40) | CA12CA1CA2CA9EP300 | |
| SCHEMBL10823574 | 0.87 | CA12 (0.45) | CA12CA1CA2CA9EP300 | |
| SCHEMBL10823370 | 0.85 | EP300 (0.43) | CA12CA1CA2CA9EP300 | |
| SCHEMBL10823454 | 0.85 | CA12 (0.41) | CA12CA1CA2CA9EP300 | |
| SCHEMBL10823538 | 0.84 | MEN1 (0.44) | CA12CA1CA2CA9EP300 | |
| SCHEMBL10823663 | 0.84 | LMNA (0.47) | EP300POLBHTTKMT2AMEN1 | |
| SCHEMBL10823738 | 0.83 | MEN1 (0.44) | CA12CA1CA2CA9EP300 | |
| SCHEMBL10823359 | 0.82 | CA12 (0.45) | CA12CA1CA2CA9EP300 | |
| SCHEMBL10823540 | 0.82 | MEN1 (0.53) | CA12CA1CA2CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |