Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 19/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823528 | 0.86 | IDH1 (0.54) | IDH1MEN1GAAG6PDKMT2A | |
| SCHEMBL10823495 | 0.86 | IDH1 (0.56) | IDH1MEN1GAAG6PDKMT2A | |
| SCHEMBL10823659 | 0.83 | IDH1 (0.53) | IDH1MEN1GAAG6PDKMT2A | |
| SCHEMBL10823391 | 0.83 | HKDC1 (0.48) | MEN1GAAKMT2A | |
| SCHEMBL10823457 | 0.81 | IDH1 (0.56) | IDH1 | |
| SCHEMBL11340304 | 0.81 | CA12 (0.41) | MEN1KMT2A | |
| SCHEMBL10823467 | 0.81 | IDH1 (0.58) | IDH1 | |
| SCHEMBL10823616 | 0.80 | IDH1 (0.57) | IDH1 | |
| SCHEMBL10823681 | 0.79 | EP300 (0.47) | MEN1GAAG6PDKMT2A | |
| SCHEMBL10823549 | 0.79 | IDH1 (0.53) | IDH1MEN1GAAG6PDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |