Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.48 |
| ▸ | EP300 | Q09472 | 2/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823681 | 0.84 | EP300 (0.47) | HKDC1EP300KAT2BKAT8LMNA | |
| SCHEMBL10823344 | 0.83 | EP300 (0.50) | HKDC1EP300LMNAMEN1KMT2A | |
| SCHEMBL10823718 | 0.83 | HKDC1 (0.48) | HKDC1EP300KAT2BKAT8LMNA | |
| SCHEMBL10823556 | 0.83 | IDH1 (0.55) | MEN1KMT2AGAA | |
| SCHEMBL11344807 | 0.81 | TIMP3 (0.48) | MEN1KMT2APOLBHPGDCA12 | |
| SCHEMBL10823378 | 0.81 | MEN1 (0.49) | LMNAMEN1KMT2AHTTGAA | |
| SCHEMBL10823667 | 0.79 | MEN1 (0.44) | HKDC1EP300KAT2BKAT8LMNA | |
| SCHEMBL10823698 | 0.78 | PRMT1 (0.55) | HKDC1EP300KAT2BKAT8LMNA | |
| SCHEMBL10823663 | 0.78 | LMNA (0.47) | EP300LMNAMEN1KMT2AHTT | |
| SCHEMBL10823694 | 0.77 | PRMT1 (0.53) | HKDC1EP300KAT2BKAT8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |