Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 18/20 | 0.53 |
| ▸ | IDH2 | P48735 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823589 | 0.96 | IDH1 (0.53) | IDH1IDH2 | |
| SCHEMBL10823696 | 0.84 | TIMP3 (0.47) | MEN1GAAKMT2A | |
| SCHEMBL10823432 | 0.83 | IDH1 (0.59) | IDH1 | |
| SCHEMBL10823686 | 0.83 | IDH1 (0.52) | IDH1IDH2 | |
| SCHEMBL11336058 | 0.83 | TIMP3 (0.46) | IDH1MEN1GAAKMT2A | |
| SCHEMBL10823363 | 0.82 | IDH1 (0.58) | IDH1IDH2 | |
| SCHEMBL10823494 | 0.82 | IDH1 (0.54) | IDH1IDH2 | |
| SCHEMBL10823584 | 0.82 | MEN1 (0.56) | IDH1MEN1GAAG6PDKMT2A | |
| SCHEMBL10823352 | 0.81 | PTGES (0.41) | IDH1MEN1GAAG6PDKMT2A | |
| SCHEMBL10823421 | 0.81 | MEN1 (0.48) | IDH1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |