Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823696 | 0.85 | TIMP3 (0.47) | EP300KAT2BKAT8KMT2AMEN1 | |
| SCHEMBL10823370 | 0.85 | EP300 (0.43) | EP300KAT2BKAT8KMT2AMEN1 | |
| SCHEMBL10823773 | 0.83 | IDH1 (0.45) | EP300KAT2BKAT8KMT2AMEN1 | |
| SCHEMBL10823472 | 0.83 | PTGES (0.46) | PTGESCYTH2KMT2AMEN1GFER | |
| SCHEMBL10823553 | 0.83 | PTGES (0.50) | PTGESKMT2AMEN1IDH1GAA | |
| SCHEMBL10823454 | 0.83 | CA12 (0.41) | EP300KAT2BKAT8KMT2AMEN1 | |
| SCHEMBL10823421 | 0.82 | MEN1 (0.48) | KMT2AMEN1HPSEIDH1ALDH1A1 | |
| SCHEMBL10823443 | 0.81 | MEN1 (0.44) | PTGESCYTH2KMT2AMEN1GFER | |
| SCHEMBL10823744 | 0.81 | PRMT1 (0.44) | PTGESCYTH2KMT2AMEN1GFER | |
| SCHEMBL10823471 | 0.81 | EP300 (0.44) | EP300KAT2BKAT8KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |