Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250451 | 0.86 | KDM4E (0.46) | KDM4EALDH1A1HTTTDP1HPGD | |
| SCHEMBL2354114 | 0.84 | TSHR (0.56) | KDM4EALDH1A1HTTTDP1HPGD | |
| SCHEMBL10341697 | 0.81 | FFAR1 (0.48) | KDM4EALDH1A1HTTTDP1HPGD | |
| SCHEMBL17284082 | 0.80 | TSHR (0.61) | KDM4EALDH1A1TDP1TSHR | |
| SCHEMBL10341726 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1HTTTDP1HPGD | |
| SCHEMBL5199927 | 0.79 | CETP (0.52) | KDM4EALDH1A1HTTTDP1HPGD | |
| SCHEMBL204914 | 0.79 | LTA4H (0.51) | KDM4EALDH1A1HTTTDP1HPGD | |
| SCHEMBL7931594 | 0.78 | FFAR1 (0.48) | KDM4EALDH1A1HTTTDP1HPGD | |
| SCHEMBL2093737 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1HTTTDP1HPGD | |
| SCHEMBL9559057 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1HTTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61053291-A | — | — | None | — | — | JP | disclosed |
| JP-S6153291-A | ORGANOSILICON COMPOUND, ITS PRODUCTION, AND INSECTICIDE COMPRISING IT AS ACTIVE INGREDIENT | SUMITOMO CHEM CO LTD | 1986-03-17 | — | — | JP | disclosed |