SCHEMBL250451

SCHEMBL250451

C[Si](C)(COCc1cccc(Oc2ccccc2)c1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
ALDH1A1 P00352 4/20 0.46
HTT P42858 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.43
CETP P11597 1/20 0.42
FFAR1 O14842 3/20 0.42
FFAR4 Q5NUL3 2/20 0.42
TRPV6 Q9H1D0 1/20 0.42
FAAH O00519 1/20 0.41
NPC1 O15118 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MMP1 P03956 1/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10341697 0.93 FFAR1 (0.48) KDM4EALDH1A1HTTTDP1HPGD
SCHEMBL10341726 0.92 KDM4E (0.40) KDM4EALDH1A1HTTTDP1HPGD
SCHEMBL204914 0.88 LTA4H (0.51) KDM4EALDH1A1HTTTDP1HPGD
SCHEMBL10824366 0.86 KDM4E (0.49) KDM4EALDH1A1HTTTDP1HPGD
SCHEMBL2354114 0.81 TSHR (0.56) KDM4EALDH1A1HTTTDP1HPGD
SCHEMBL9331042 0.80 ALDH1A1 (0.38) KDM4EALDH1A1HTTTDP1HPGD
SCHEMBL7228238 0.77 FDFT1 (0.46) KDM4EALDH1A1HTTTDP1HPGD
SCHEMBL5199927 0.75 CETP (0.52) KDM4EALDH1A1HTTTDP1HPGD
SCHEMBL7931594 0.74 FFAR1 (0.48) KDM4EALDH1A1HTTTDP1HPGD
SCHEMBL7169249 0.74 KCNH2 (0.41) KDM4EALDH1A1HTTTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012076699-A1 BIOCIDE MICROCAPSULE FORMULATIONS CONTAINING STABILISED IODINE-CONTAINING COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2012-06-14 WO claimed
EP-2462805-A1 Formulations containing stabilised compounds containing iodine LANXESS Deutschland GmbH (DE) 2012-06-13 EP claimed
EP-0884149-A2 Microbicidal agents BAYER AG (DE) 1998-12-16 EP claimed
EP-0458060-B1 Agent for preserving wood and wooden materials DESOWAG MATERIALSCHUTZ GMBH (DE) 1995-10-11 EP claimed
EP-0458061-B1 Agent for preserving wood and wooden materials DESOWAG MATERIALSCHUTZ GMBH (DE) 1995-10-11 EP claimed
US-5196407-A Fungicide, stabilizer, diluent DESOWAG MATERIALSCHUTZ GMBH (DE) 1993-03-23 US claimed
EP-0458061-A1 Agent for preserving wood and wooden materials DESOWAG GmbH (DE) 1991-11-27 EP claimed
EP-0458060-A1 Agent for preserving wood and wooden materials DESOWAG GmbH (DE) 1991-11-27 EP claimed
JP-61263988-A None JP disclosed
US-10798940-B2 Penflufen polymer particles LANXESS DEUTSCHLAND GMBH (DE) 2020-10-13 US disclosed
EP-3428148-B1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) 2020-07-08 EP disclosed
EP-3344663-B1 POLYMER PARTICLE CONTAINING PENFLUFEN LANXESS DEUTSCHLAND GMBH (DE) 2020-02-19 EP disclosed
EP-3344664-B1 BIOCIDAL MIXTURES LANXESS DEUTSCHLAND GMBH (DE) 2019-09-25 EP disclosed
EP-3428148-A1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF Merial, Inc. (US) 2019-01-16 EP disclosed
EP-0458060-A1 Agent for preserving wood and wooden materials DESOWAG GmbH (DE) 1991-11-27 EP disclosed
EP-0458061-A1 Agent for preserving wood and wooden materials DESOWAG GmbH (DE) 1991-11-27 EP disclosed
EP-0202893-B1 PESTICIDAL SILYLMETHYL ETHER COMPOUNDS SHIONOGI & CO., LTD. (JP) 1990-01-03 EP disclosed
US-4663314-A PESTICIDES SHIONOGI & CO., LTD. (JP) 1987-05-05 US disclosed
EP-0202893-A2 Pesticidal silylmethyl ether compounds SHIONOGI & CO., LTD. (JP) 1986-11-26 EP disclosed
JP-S61263988-A SILYL-SUBSTITUTED ETHER AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME SHIONOGI & CO LTD 1986-11-21 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10798940-B2 Penflufen polymer particles FAP, PUF60, MATR3 KDM4E 1136/4885ALDH1A1 194/4885HTT 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.