SCHEMBL204914

SCHEMBL204914

CCOc1ccc([Si](C)(C)COCc2cccc(Oc3ccccc3)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.51
FFAR1 O14842 5/20 0.46
FFAR4 Q5NUL3 1/20 0.44
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
TP53 P04637 1/20 0.42
PKM P14618 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.42
CETP P11597 2/20 0.42
MGLL Q99685 1/20 0.40
HTT P42858 2/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250451 0.88 KDM4E (0.46) FFAR1FFAR4KDM4EALDH1A1SMN1; SMN2
SCHEMBL10341697 0.85 FFAR1 (0.48) FFAR1FFAR4KDM4EALDH1A1SMN1; SMN2
SCHEMBL10341726 0.84 KDM4E (0.40) FFAR1FFAR4KDM4EALDH1A1SMN1; SMN2
SCHEMBL10489494 0.83 LTA4H (0.43) LTA4HFFAR1KDM4EALDH1A1SMN1; SMN2
SCHEMBL7525556 0.82 LTA4H (0.54) LTA4HFFAR1FFAR4KDM4EALDH1A1
SCHEMBL10554911 0.81 LTA4H (0.51) LTA4HFFAR1FFAR4KDM4EALDH1A1
SCHEMBL6779563 0.81 LTA4H (0.51) LTA4HFFAR1FFAR4CETPMGLL
SCHEMBL9331042 0.80 ALDH1A1 (0.38) FFAR1FFAR4KDM4EALDH1A1TDP1
SCHEMBL8858271 0.79 LTA4H (0.46) LTA4HKDM4EALDH1A1SMN1; SMN2TP53
SCHEMBL10824366 0.79 KDM4E (0.49) FFAR1FFAR4KDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2462805-A1 Formulations containing stabilised compounds containing iodine LANXESS Deutschland GmbH (DE) 2012-06-13 EP claimed
EP-0458060-B1 Agent for preserving wood and wooden materials DESOWAG MATERIALSCHUTZ GMBH (DE) 1995-10-11 EP claimed
EP-0458061-B1 Agent for preserving wood and wooden materials DESOWAG MATERIALSCHUTZ GMBH (DE) 1995-10-11 EP claimed
US-5196407-A Fungicide, stabilizer, diluent DESOWAG MATERIALSCHUTZ GMBH (DE) 1993-03-23 US claimed
JP-60123491-A None JP disclosed
US-20250281926-A1 SAMPLE MANIPULATION AND ASSAY WITH RAPID TEMPERATURE CHANGE ESSENLIX CORPORATION (US) 2025-09-11 US disclosed
US-12270810-B2 QMAX assay and applications (II) ESSENLIX CORPORATION (US) 2025-04-08 US disclosed
US-20250099965-A1 RAPID SAMPLE TEMPERATURE CHANGING FOR ASSAYING ESSENLIX CORPORATION (US) 2025-03-27 US disclosed
US-12226769-B2 Sample manipulation and assay with rapid temperature change ESSENLIX CORPORATION (US) 2025-02-18 US disclosed
US-12064771-B2 Rapid sample temperature changing for assaying ESSENLIX CORPORATION (US) 2024-08-20 US disclosed
US-11796428-B2 Compressed open flow assay and use ESSENLIX CORPORATION (US) 2023-10-24 US disclosed
CN-110770572-B Colorimetric assay ESSENLIX公司 2023-08-18 CN disclosed
EP-0547480-A1 Microbicidal agents BAYER AG (DE) 1993-06-23 EP disclosed
US-5196407-A Fungicide, stabilizer, diluent DESOWAG MATERIALSCHUTZ GMBH (DE) 1993-03-23 US disclosed
US-5028706-A Process for the preparation of halosilanes HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-02 US disclosed
EP-0350804-A2 Process for the preparation of halosilanes HOECHST AKTIENGESELLSCHAFT (DE) 1990-01-17 EP disclosed
EP-0202893-B1 PESTICIDAL SILYLMETHYL ETHER COMPOUNDS SHIONOGI & CO., LTD. (JP) 1990-01-03 EP disclosed
US-4663314-A PESTICIDES SHIONOGI & CO., LTD. (JP) 1987-05-05 US disclosed
EP-0202893-A2 Pesticidal silylmethyl ether compounds SHIONOGI & CO., LTD. (JP) 1986-11-26 EP disclosed
JP-S60123491-A ORGANOSILICON COMPOUND, ITS PREPARATION, AND INSECTICIDE CONTAINING IT AS ACTIVE INGREDIENT SUMITOMO CHEM CO LTD 1985-07-02 JP disclosed