SCHEMBL10824435

SCHEMBL10824435

OCC(OC(CO)c1c(Br)cc(Br)cc1Br)c1c(Br)cc(Br)cc1Br

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824436 0.65 TSHR (0.37) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL4091711 0.65 TDP1 (0.45) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL7786052 0.64 CYP3A4 (0.40) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL9816242 0.63 CYP3A4 (0.30) CYP3A4TSHRTDP1
SCHEMBL7152624 0.62 TDP1 (0.39) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL10711308 0.61 TSHR (0.54) TSHR
SCHEMBL11207294 0.61 TSHR (0.33) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL10338472 0.61 CYP3A4 (0.32) CYP3A4TSHRTDP1
SCHEMBL11045534 0.61 GABRA1 (0.44) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL1046753 0.61 CYP3A4 (0.48) CYP3A4TSHRTDP1GABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61091231-A None JP disclosed
JP-61085444-A None JP disclosed
JP-61085453-A None JP disclosed
JP-S6191231-A PRODUCTION OF FLAME RETARDANT HITACHI CHEM CO LTD 1986-05-09 JP disclosed
JP-S6185444-A PRODUCTION OF FLAME-RETARDANT PHENOLIC RESIN LAMINATE HITACHI CHEM CO LTD 1986-05-01 JP disclosed
JP-S6185453-A PRODUCTION OF FLAME-RETARDANT HITACHI CHEM CO LTD 1986-05-01 JP disclosed