Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684807 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL9684696 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL9683704 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL9683619 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL13588569 | 0.79 | MAPT (0.50) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL28189241 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL7399387 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL9684761 | 0.76 | MAPT (0.40) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL9683608 | 0.76 | XBP1 (0.47) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL9684731 | 0.76 | ADRB2 (0.44) | ALDH1A1MAPTKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61083180-A | — | — | None | — | — | JP | disclosed |
| JP-S6183180-A | ISOCHROMAN DERIVATIVE AND ITS PREPARATION | MORISHITA SEIYAKU KK | 1986-04-26 | — | — | JP | disclosed |