Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683619 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GAAL3MBTL1MAPTKMT2A | |
| SCHEMBL9683704 | 1.00 | ALDH1A1 (0.44) | ALDH1A1GAAL3MBTL1MAPTKMT2A | |
| SCHEMBL9684785 | 0.92 | ADRB2 (0.44) | ALDH1A1GAAL3MBTL1MAPTKMT2A | |
| SCHEMBL9683608 | 0.92 | XBP1 (0.47) | ALDH1A1GAAL3MBTL1MAPTKMT2A | |
| SCHEMBL9684731 | 0.92 | ADRB2 (0.44) | ALDH1A1GAAL3MBTL1MAPTKMT2A | |
| SCHEMBL9683778 | 0.91 | KDM4E (0.45) | ALDH1A1GAAL3MBTL1MAPTKMT2A | |
| SCHEMBL9683750 | 0.91 | HTR1A (0.43) | ALDH1A1GAAL3MBTL1MAPTKMT2A | |
| SCHEMBL9682923 | 0.89 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2ALMNACYP1A2 | |
| SCHEMBL9684717 | 0.89 | ADRB2 (0.43) | ALDH1A1GAAMAPTKMT2ALMNA | |
| SCHEMBL9683757 | 0.89 | ADRB2 (0.50) | CYP2D6ADRB1ADRB3TSHRADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128369-A | Antiallergens, bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0404197-A2 | Arylalkylamine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |