Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | KDM1A | O60341 | 3/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.49 |
| ▸ | NAMPT | P43490 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31022619 | 0.86 | NAMPT (0.66) | RAB9AKDM1ARCOR1NAMPTSMN1; SMN2 | |
| SCHEMBL31650535 | 0.83 | ALDH1A1 (0.51) | NAMPTSMN1; SMN2ALDH1A1PRMT5WDR77 | |
| SCHEMBL2514323 | 0.83 | NAMPT (0.42) | RAB9AKDM1ARCOR1NAMPTSMN1; SMN2 | |
| SCHEMBL31650777 | 0.80 | NAMPT (0.54) | RAB9ANAMPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9199617 | 0.79 | ATM (0.51) | RAB9ASMN1; SMN2HTTNPC1MEN1 | |
| SCHEMBL20854623 | 0.79 | SNCA (0.46) | RAB9ANAMPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL23406103 | 0.79 | PTPN2 (0.46) | RAB9ANAMPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL20653377 | 0.79 | HPGDS (0.44) | RAB9AALDH1A1HTTNPC1TP53 | |
| SCHEMBL31650395 | 0.79 | SMN1; SMN2 (0.64) | RAB9ASMN1; SMN2ALDH1A1HTTNPC1 | |
| SCHEMBL20741592 | 0.77 | MCHR1 (0.48) | RAB9APRMT5WDR77KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61178968-A | — | — | None | — | — | JP | disclosed |
| US-20230183213-A1 | 5-MEMBERED HETEROARYL CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV | ASSEMBLY BIOSCIENCES, INC. | 2023-06-15 | — | — | US | disclosed |
| JP-S61178968-A | PRODUCTION OF 1-SUBSTITUTED IMIDAZOLE-5-CARBOXAMIDE DERIVATIVE | NIPPON CARBIDE IND CO LTD | 1986-08-11 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183213-A1 | 5-MEMBERED HETEROARYL CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV | HCCS, HAVCR2, MAVS | RAB9A 1662/4885KDM1A 2772/4885RCOR1 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.