Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2326248 | 0.83 | MAPT (0.64) | MAPTPOLBPIN1ALDH1A1GAA | |
| SCHEMBL7168591 | 0.82 | MAPT (0.67) | MAPTPOLBPIN1ALDH1A1GAA | |
| SCHEMBL9818964 | 0.82 | MAPT (0.67) | MAPTPOLBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13720687 | 0.80 | MAPT (0.64) | MAPTPOLBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18162301 | 0.79 | PIN1 (0.51) | MAPTPIN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11291316 | 0.79 | PIN1 (0.51) | MAPTPOLBPIN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13749241 | 0.79 | MAPT (0.67) | MAPTPOLBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7406297 | 0.78 | MAPT (0.59) | MAPTPOLBPIN1ALDH1A1GAA | |
| SCHEMBL8486512 | 0.77 | PIN1 (0.55) | MAPTPIN1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL1020458 | 0.77 | MAPT (0.61) | MAPTPOLBPIN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61166860-A | — | — | None | — | — | JP | disclosed |
| JP-S61166860-A | NONALLERGIC AZO PIGMENT AND ITS PRODUCTION | SHISEIDO CO LTD | 1986-07-28 | — | — | JP | disclosed |