SCHEMBL8486512

SCHEMBL8486512

O=[N+]([O-])c1ccccc1Oc1ccc2ccccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.55
HPGD P15428 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
GAA P10253 2/20 0.53
RCE1 Q9Y256 1/20 0.53
ALDH1A1 P00352 6/20 0.51
TDP1 Q9NUW8 1/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
RECQL P46063 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
LTA4H P09960 1/20 0.49
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
HTT P42858 3/20 0.49
MAPT P10636 3/20 0.48
LMNA P02545 2/20 0.48
HSPB1 P04792 1/20 0.48
KMT2A Q03164 2/20 0.47
F10 P00742 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9390091 0.97 HPGD (0.54) PIN1HPGDL3MBTL1GAARCE1
SCHEMBL1340761 0.86 HSPB1 (0.59) PIN1HPGDL3MBTL1GAARCE1
SCHEMBL9389173 0.86 L3MBTL1 (0.51) PIN1HPGDL3MBTL1GAARCE1
SCHEMBL10145841 0.86 MAPT (0.49) PIN1HPGDL3MBTL1GAAALDH1A1
SCHEMBL10360452 0.84 L3MBTL1 (0.59) HPGDL3MBTL1ALDH1A1TDP1NPC1
SCHEMBL28219324 0.84 L3MBTL1 (0.62) HPGDL3MBTL1GAAALDH1A1TDP1
SCHEMBL10824979 0.83 PDE7A (0.66) PIN1HPGDGAAALDH1A1TDP1
SCHEMBL25747670 0.83 ALDH1A1 (0.46) PIN1HPGDL3MBTL1GAAALDH1A1
SCHEMBL9447250 0.83 ALDH1A1 (0.58) PIN1HPGDL3MBTL1GAAALDH1A1
SCHEMBL9853579 0.81 PIN1 (0.47) PIN1HPGDL3MBTL1GAARCE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102060790-B Quinoxaline double N-oxide derivative ligand and application thereof in promotion on copper-catalyzed C-O coupling reaction SHANGHAI INST TECHNOLOGY 2013-01-09 CN disclosed
CN-102060790-A Quinoxaline double N-oxide derivative ligand and application thereof to promotion on copper-catalyzed C-O coupling reaction SHANGHAI INST TECHNOLOGY 2011-05-18 CN disclosed
US-5962436-A AGRICULTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-10-05 US disclosed
CN-1182423-A Fungicidal cyclic amides DU PONT (US) 1998-05-20 CN disclosed
EP-0810997-A1 FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-12-10 EP disclosed
WO-1996026191-A1 FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-29 WO disclosed