Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 17/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10825515 | 0.71 | RAD52 (0.48) | GRM5HRH3 | |
| SCHEMBL29397882 | 0.71 | ADRA2A (0.49) | GRM5 | |
| Dimethylamine SCHEMBL10825447 | 0.71 | DPP4 (0.43) | GRM5 | |
| SCHEMBL10764703 | 0.69 | GRAMD1A (0.43) | MEN1KMT2A | |
| SCHEMBL10825441 | 0.67 | GRM5 (0.38) | GRM5MEN1KMT2AHRH3 | |
| SCHEMBL30717388 | 0.66 | GRM5 (0.36) | GRM5 | |
| SCHEMBL976666 | 0.63 | HDAC3 (0.40) | GRM5 | |
| SCHEMBL10825660 | 0.62 | HDAC2 (0.33) | — | |
| SCHEMBL10825418 | 0.61 | POLB (0.44) | GRM5 | |
| SCHEMBL10756470 | 0.61 | TSHR (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4624956-A | Ulcer and gastric secretion inhibiting 4,5,6,7-tetrahydrothiazole[5,4-c]pyridine derivatives | FARMITALIA CARLO ERBA (IT) | 1986-11-25 | — | — | US | disclosed |