Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | HPGD | P15428 | 7/20 | 0.61 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CASP9 | P55211 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28814563 | 0.81 | KDM4E (0.61) | KDM4EHPGDPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13299346 | 0.81 | KDM4E (0.65) | KDM4EHPGDPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL460609 | 0.78 | KDM4E (0.61) | KDM4EHPGDPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29486731 | 0.78 | KDM4E (0.61) | KDM4EHPGDPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25548538 | 0.78 | KDM4E (0.61) | KDM4EHPGDPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL459011 | 0.77 | KDM4E (1.00) | KDM4EHPGDPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9703950 | 0.77 | ALOX5 (0.42) | KDM4EHPGDPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28395541 | 0.76 | KDM4E (0.59) | KDM4EHPGDPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10775777 | 0.76 | KDM4E (0.59) | KDM4EHPGDPARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11545990 | 0.76 | KDM4E (0.35) | KDM4EHPGDPARP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108686907-A | The system and method for coating on curing optical fiber | 上海臻辉光电技术有限公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-102089316-B | Liquid mixtures of oxyalkylene-bridged bis-and triphosphites | BASF SE | 2013-12-25 | — | — | CN | disclosed |
| US-4614753-A | Light-resistant and weather-proof polyolefin foams | DYNAMIT NOBEL AG (DE) | 1986-09-30 | — | — | US | disclosed |
| US-4590221-A | WITH PHENOLIC ANTIOXIDANT, BENZOPHENONES AND/OR BENZOTR<IAZOLES, AND STERICALLY HINDERED AMINES | DYNAMIT NOBEL AG (DE) | 1986-05-20 | — | — | US | disclosed |