SCHEMBL460609

SCHEMBL460609

Oc1cccc2nn(-c3ccccc3)nc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.61
HPGD P15428 5/20 0.61
PARP1 P09874 1/20 0.59
ALDH1A1 P00352 7/20 0.46
RAB9A P51151 6/20 0.46
KMT2A Q03164 5/20 0.46
MAPT P10636 3/20 0.46
GAA P10253 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ACHE P22303 1/20 0.45
FGFR1 P11362 1/20 0.45
NPC1 O15118 5/20 0.43
MEN1 O00255 3/20 0.43
STAT1 P42224 1/20 0.43
POLB P06746 2/20 0.43
CYP1A2 P05177 1/20 0.42
SMN1; SMN2 Q16637 4/20 0.41
LMNA P02545 2/20 0.41
BLM P54132 1/20 0.41
CASP9 P55211 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28139129 0.81 POLB (0.62) KDM4EHPGDPARP1ALDH1A1RAB9A
SCHEMBL13299346 0.81 KDM4E (0.65) KDM4EHPGDPARP1ALDH1A1RAB9A
SCHEMBL10591508 0.80 KDM4E (0.53) KDM4EHPGDPARP1ALDH1A1RAB9A
SCHEMBL8680274 0.78 CNR1 (0.40) KDM4EHPGDPARP1ALDH1A1RAB9A
SCHEMBL28814563 0.78 KDM4E (0.61) KDM4EHPGDPARP1ALDH1A1RAB9A
SCHEMBL29486731 0.78 KDM4E (0.61) KDM4EHPGDPARP1ALDH1A1RAB9A
SCHEMBL25548538 0.78 KDM4E (0.61) KDM4EHPGDPARP1ALDH1A1RAB9A
SCHEMBL10825713 0.78 KDM4E (0.61) KDM4EHPGDPARP1ALDH1A1RAB9A
SCHEMBL459011 0.77 KDM4E (1.00) KDM4EHPGDPARP1ALDH1A1RAB9A
SCHEMBL28395541 0.76 KDM4E (0.59) KDM4EHPGDPARP1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 415 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119403875-A Acrylonitrile styrene acrylate copolymer compositions with improved UV resistance 英力士苯领集团股份公司 2025-02-07 CN disclosed
CN-119173576-A Acrylonitrile-styrene-acrylate (ASA) copolymer compositions with low UV absorber content and good UV resistance 英力士苯领集团股份公司 2024-12-20 CN disclosed
CN-119053565-A Radiation curable composition for coating optical fibers 科思创(荷兰)有限公司 2024-11-29 CN disclosed
CN-119032070-A Low volatility radiation curable compositions for coating optical fibers 科思创(荷兰)有限公司 2024-11-26 CN disclosed
CN-119032069-A Low volatility radiation curable compositions for coating optical fibers 科思创(荷兰)有限公司 2024-11-26 CN disclosed
CN-116239949-B Radiation curable composition for coating optical fibers and coatings produced therefrom 科思创(荷兰)有限公司 2024-07-05 CN disclosed
US-11964906-B2 Radiation curable compositions for coating optical fiber COVESTRO (NETHERLANDS) B.V. (NL) 2024-04-23 US disclosed
US-11952453-B2 Radiation curable compositions for coating optical fiber and the coatings produced therefrom COVESTRO (NETHERLANDS) B.V (NL) 2024-04-09 US disclosed
US-11932571-B2 Radiation curable compositions for coating optical fiber with enhanced high-speed processability Covestro (Netherland) B.V. (NL) 2024-03-19 US disclosed
CN-114144386-B Radiation curable composition for coating optical fibers with enhanced high speed processability 科思创(荷兰)有限公司 2023-11-17 CN disclosed
US-20020169429-A1 Wettable polyolefin fibers and fabrics TECHMER PM, LLC 2002-11-14 US disclosed
WO-2002088240-A1 POLYACETAL MOLDED ARTICLES STABILIZED AGAINST DISCOLORATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-11-07 WO disclosed
US-20020161123-A1 Dyeable polyolefin fibers and rabrics CIBA SPECIALTY CHEMICALS CORP. 2002-10-31 US disclosed
US-20020137856-A1 Polyester compositions of low residual aldehyde content CIBA SPECIALTY CHEMICALS CORP. 2002-09-26 US disclosed
US-20020106413-A1 Mixtures of phenolic and inorganic materials with antimicrobial activity CIBA CORPORATION 2002-08-08 US disclosed
EP-1038912-A2 High molecular weight hindered hydrocarbyloxyamine stabilizers Ciba SC Holding AG (CH) 2000-09-27 EP disclosed
EP-0581942-A1 ALUMINUM WHEEL CLEARCOAT WITH UV ADDITIVE TO RETARD FILIFORM CORROSION MORTON INTERNATIONAL, INC. (US) 1994-02-09 EP disclosed
WO-1993013875-A1 ALUMINUM WHEEL CLEARCOAT WITH UV ADDITIVE TO RETARD FILIFORM CORROSION MORTON INTERNATIONAL, INC. (US) 1993-07-22 WO disclosed
WO-1989005840-A1 ADHESIVE ACRYLIC FORMULATION WHICH PRODUCES A HARDENED ADHESIVE JOINT SOCIETE NATIONALE ELF AQUITAINE (FR) 1989-06-29 WO disclosed
EP-0031302-A2 Benzotriazole UV absorbers, process for their preparation and stabilized mixtures CIBA-GEIGY AG (CH) 1981-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020106413-A1 Mixtures of phenolic and inorganic materials with antimicrobial activity CUTA, PUF60, TYR KDM4E 3124/4885HPGD 3331/4885PARP1 260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.