SCHEMBL459011

SCHEMBL459011

c1ccc(-n2nc3ccccc3n2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 1.00
HPGD P15428 7/20 1.00
ALDH1A1 P00352 9/20 0.63
NPC1 O15118 6/20 0.63
RAB9A P51151 6/20 0.63
KMT2A Q03164 5/20 0.63
MEN1 O00255 4/20 0.63
MAPT P10636 3/20 0.63
STAT1 P42224 1/20 0.63
HTT P42858 5/20 0.59
SMN1; SMN2 Q16637 6/20 0.53
LMNA P02545 2/20 0.53
POLB P06746 1/20 0.53
BLM P54132 1/20 0.53
CASP9 P55211 1/20 0.53
CASP6 P55212 1/20 0.53
CASP8 Q14790 1/20 0.53
PARP1 P09874 1/20 0.52
TSHR P16473 1/20 0.48
HSD17B10 Q99714 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28395544 0.85 KDM4E (0.74) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL17155207 0.85 KDM4E (0.72) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL18593568 0.84 KDM4E (0.73) KDM4EHPGDALDH1A1NPC1RAB9A
Diethylamine SCHEMBL10950327 0.83 KDM4E (0.69) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL14799765 0.82 KDM4E (0.70) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL13703267 0.82 KDM4E (0.68) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL19794402 0.80 KDM4E (0.67) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL2670040 0.80 KDM4E (0.67) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL19993879 0.80 KDM4E (0.67) KDM4EHPGDALDH1A1NPC1RAB9A
SCHEMBL1428276 0.80 KDM4E (0.67) KDM4EHPGDALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 817 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497490-B2 Millable silicone rubber composition, silicone rubber cured product, and electrically-insulating member for power cable connection SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-16 US claimed
CN-119899503-A Degradable plastic woven bag and manufacturing method thereof 云南昆发塑业有限公司 2025-04-29 CN claimed
US-12252474-B2 Ultraviolet absorber having excellent heat resistance and long-wavelength absorption MIYOSHI OIL & FAT CO., LTD. (JP) 2025-03-18 US claimed
US-12110381-B2 Resin molding material, method for producing same, and method for producing resin member or the like MIYOSHI OIL & FAT CO., LTD. (JP) 2024-10-08 US claimed
CN-114269861-B Mixing type silicone rubber composition, silicone rubber cured product, and electric insulating member for power cable connection 信越化学工业株式会社 2024-03-19 CN claimed
CN-113728070-B Ultraviolet absorber excellent in heat resistance and long-wavelength absorption 三吉油脂株式会社 2024-03-08 CN claimed
CN-113272263-B Glass sheet with coating film and composition for forming the same 日本板硝子株式会社 2023-11-28 CN claimed
CN-116888232-A Adhesive for display device and adhesive sheet using same 株式会社巴川制纸所 2023-10-13 CN claimed
CN-113088091-B High-temperature mixed silicone rubber for rail transit vehicle cables and preparation method thereof 新安天玉有机硅有限公司 2023-01-03 CN claimed
US-20220162174-A1 ULTRAVIOLET ABSORBER HAVING EXCELLENT HEAT RESISTANCE AND LONG-WAVELENGTH ABSORPTION MIYOSHI OIL & FAT CO., LTD. (JP) 2022-05-26 US claimed
US-4940469-A Low-foaming composition for finishing synthetic fibres: dye or optical brightener or ultra-violet absorber and alkylene-diamide:ethylene-distearamide CIBA-GEIGY CORPORATION (US) 1990-07-10 US claimed
EP-0160246-B1 A METHOD FOR PRODUCING A 2-PHENYLBENZOTRIAZOLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-01-24 EP claimed
US-4835284-A Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1989-05-30 US claimed
US-4798427-A Apparatus for use in sunbathing SEVENDART LIMITED, A LIMITED COMPANY OF U.K. (GB) 1989-01-17 US claimed
US-4780541-A Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1988-10-25 US claimed
EP-0263905-A1 Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1988-04-20 EP claimed
EP-0259530-A1 Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1988-03-16 EP claimed
EP-0257151-A1 Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1988-03-02 EP claimed
EP-0160246-A1 A method for producing A 2-phenylbenzotriazole SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-06 EP claimed
US-4247628-A STABLE CYAN DYE IMAGE FROM NAPHTHOL OR PHENOL COUPLERS, 2-(2'-(R-O-)PHENYL)BENZOTRIAZOLES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-01-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220162174-A1 ULTRAVIOLET ABSORBER HAVING EXCELLENT HEAT RESISTANCE AND LONG-WAVELENGTH ABSORPTION HSPB1, HEATR1, TAS1R3 KDM4E 1842/4885HPGD 1139/4885ALDH1A1 255/4885
US-12252474-B2 Ultraviolet absorber having excellent heat resistance and long-wavelength absorption HSPB1, HEATR1, TAS1R3 KDM4E 1842/4885HPGD 1139/4885ALDH1A1 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.