Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.76 |
| ▸ | DRD3 | P35462 | 10/20 | 0.76 |
| ▸ | DRD4 | P21917 | 2/20 | 0.62 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | HRH2 | P25021 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | TEK | Q02763 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10826542 | 0.92 | DRD2 (0.69) | DRD2DRD3DRD4LMNAHRH1 | |
| Fumaric Acid SCHEMBL10826547 | 0.92 | DRD2 (0.69) | DRD2DRD3DRD4LMNAHRH1 | |
| Hydrochloric Acid SCHEMBL10827491 | 0.91 | DRD2 (0.71) | DRD2DRD3LMNAHDAC4HDAC1 | |
| SCHEMBL10826820 | 0.86 | DRD2 (0.68) | DRD2DRD3LMNAHDAC4HDAC1 | |
| SCHEMBL10756632 | 0.85 | TMEM97 (0.72) | DRD2DRD3DRD4TMEM97SIGMAR1 | |
| SCHEMBL9661704 | 0.85 | DRD2 (0.63) | DRD2DRD3HTR2ASLC6A4 | |
| SCHEMBL7154331 | 0.84 | DRD2 (0.80) | DRD2DRD3DRD4TMEM97SIGMAR1 | |
| SCHEMBL22321657 | 0.83 | DRD2 (0.65) | DRD2DRD3LMNAHDAC4HDAC1 | |
| SCHEMBL7371815 | 0.82 | DRD2 (0.84) | DRD2DRD3DRD4TMEM97SIGMAR1 | |
| SCHEMBL9661746 | 0.82 | DRD2 (0.64) | DRD2DRD3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4591590-A | ANTIALLERGINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-27 | — | — | US | disclosed |
| EP-0113226-A1 | Benzhydrylpiperazine derivatives, processes for the preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-11 | — | — | EP | disclosed |