SCHEMBL7154331

SCHEMBL7154331

O=C(NCCCCCN1CCN(CCCNC(=O)c2ccccc2)CC1)c1ccc(Cl)cc1

nearest known ligand 0.80

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 8/20 0.80
DRD4 P21917 4/20 0.80
DRD3 P35462 8/20 0.74
TMEM97 Q5BJF2 1/20 0.69
SIGMAR1 Q99720 1/20 0.69
ADRA1A P35348 1/20 0.64
SLC6A4 P31645 1/20 0.62
KDM4E B2RXH2 1/20 0.62
ALDH1A1 P00352 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10724181 0.93 DRD2 (0.75) DRD2DRD4DRD3TMEM97SIGMAR1
SCHEMBL10723691 0.91 ALDH1A1 (0.72) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL10720221 0.91 DRD2 (0.72) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL10749846 0.91 DRD2 (0.72) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL10720274 0.91 DRD2 (0.72) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL10723885 0.91 DRD2 (0.72) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL10756632 0.91 TMEM97 (0.72) DRD2DRD4DRD3TMEM97SIGMAR1
SCHEMBL10723842 0.91 DRD2 (0.72) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL7132544 0.89 DRD2 (0.74) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL10720845 0.88 ALDH1A1 (0.76) DRD2DRD4DRD3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US claimed
EP-1149877-B1 Decolorizable ink composition and ink jet printer using the ink composition RICOH KK (JP) 2003-06-11 EP disclosed
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US disclosed
US-20020175982-A1 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2002-11-28 US disclosed
EP-1149877-A1 Decolorizable ink composition and ink jet printer using the ink composition Ricoh Company, Ltd. (JP) 2001-10-31 EP disclosed
US-4665410-A THERMOGRAPHY RICOH COMPANY, LTD. (JP) 1987-05-12 US disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed