Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.84 |
| ▸ | DRD4 | P21917 | 4/20 | 0.84 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.76 |
| ▸ | DRD3 | P35462 | 6/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.71 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369877 | 0.91 | DRD3 (0.77) | DRD2DRD4DRD3HTR1APOLB | |
| SCHEMBL10756632 | 0.88 | TMEM97 (0.72) | DRD2DRD4SLC6A4DRD3ADRA1A | |
| SCHEMBL7154331 | 0.88 | DRD2 (0.80) | DRD2DRD4SLC6A4DRD3ADRA1A | |
| SCHEMBL31061220 | 0.87 | DRD3 (0.84) | DRD2DRD4DRD3HTR1APOLB | |
| SCHEMBL18507057 | 0.86 | DRD3 (0.70) | DRD2DRD4SLC6A4DRD3HTR1A | |
| SCHEMBL7369645 | 0.85 | KDM4E (0.70) | DRD2DRD4SLC6A4DRD3POLB | |
| SCHEMBL10724181 | 0.83 | DRD2 (0.75) | DRD2DRD4DRD3ADRA1ATMEM97 | |
| SCHEMBL2355678 | 0.83 | DRD3 (0.72) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL10720845 | 0.83 | ALDH1A1 (0.76) | DRD2DRD4DRD3HTR1APOLB | |
| SCHEMBL10826554 | 0.82 | DRD2 (0.76) | DRD2DRD4SLC6A4DRD3TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714292-A4 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | CAMBRIDGE NEUROSCIENCE INC (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0714292-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1996-06-05 | — | — | EP | claimed |
| WO-1995000131-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | CAMBRIDGE NEUROSCIENCE, INCORPORATED (US) | 1995-01-05 | — | — | WO | claimed |