Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10827666 | 0.92 | ALDH1A1 (0.45) | TSHRPLA2G1BHSD17B10ATG4BALDH1A1 | |
| SCHEMBL10827062 | 0.85 | CTSD (0.45) | TSHRPLA2G1BHSD17B10ATG4BALDH1A1 | |
| SCHEMBL10827069 | 0.78 | CYP3A4 (0.46) | TSHRALOX15L3MBTL1KMT2AMEN1 | |
| SCHEMBL10828432 | 0.78 | ALDH1A1 (0.43) | TSHRALDH1A1ALOX15L3MBTL1HTT | |
| SCHEMBL10827144 | 0.78 | ALDH1A1 (0.42) | TSHRALDH1A1ALOX15L3MBTL1HTT | |
| SCHEMBL10827380 | 0.77 | PDE10A (0.48) | HSD17B10ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL10828440 | 0.73 | NPSR1 (0.45) | TSHRHSD17B10ALDH1A1L3MBTL1HTT | |
| SCHEMBL10827385 | 0.69 | KDM4E (0.44) | TSHRALDH1A1ALOX15L3MBTL1HTT | |
| SCHEMBL10827671 | 0.65 | DPP4 (0.43) | TSHRHSD17B10ALDH1A1HTTKMT2A | |
| SCHEMBL22736786 | 0.62 | ALOX15 (0.48) | TSHRPLA2G1BHSD17B10ATG4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605657-A | 4-quinazalone fungicides | CHEVRON RESEARCH COMPANY (US) | 1986-08-12 | — | — | US | disclosed |