Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 9/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14941344 | 0.86 | CTSS (0.50) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL2405498 | 0.84 | CA1 (0.46) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL5450014 | 0.84 | CTSK (0.50) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL3212391 | 0.84 | CA1 (0.46) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL9787671 | 0.83 | CTSS (0.59) | CTSKCA1CA2CA7CTSS | |
| SCHEMBL2402020 | 0.82 | CA1 (0.45) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL5045442 | 0.82 | CA1 (0.45) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL6826879 | 0.81 | CA1 (0.44) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL2401413 | 0.81 | CTSK (0.44) | CTSKCA1CA2CA7CYP2D6 | |
| SCHEMBL2401238 | 0.81 | CTSK (0.52) | CTSKCA1CA2CA7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596790-A | Pharmaceuticals | NYEGAARD & CO. A/S (NO) | 1986-06-24 | — | — | US | disclosed |
| EP-0156063-A2 | Hypoglycaemic tetrapeptides | Reichelt, Karl Ludvig (NO) | 1985-10-02 | — | — | EP | disclosed |