Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 7/20 | 0.56 |
| ▸ | CACNA1F | O60840 | 6/20 | 0.56 |
| ▸ | CACNA1D | Q01668 | 6/20 | 0.56 |
| ▸ | CACNA1S | Q13698 | 6/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31059898 | 0.88 | ADORA3 (0.73) | ADORA3CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10830248 | 0.83 | CACNA1F (0.66) | ADORA3CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7047706 | 0.83 | CACNA1F (0.66) | ADORA3CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10830900 | 0.83 | ALDH1A1 (0.74) | ADORA3TSHRKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL10830852 | 0.82 | ADORA3 (0.72) | ADORA3CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10830230 | 0.82 | ADORA3 (0.68) | ADORA3CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10830910 | 0.81 | ADORA3 (0.67) | ADORA3CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL3027412 | 0.81 | ADORA3 (0.89) | ADORA3CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL10830242 | 0.80 | ADORA3 (0.65) | ADORA3CACNA1CCACNA1FCACNA1DCACNA1S | |
| Hydrochloric Acid SCHEMBL7245633 | 0.79 | ADORA3 (0.72) | ADORA3CACNA1CCACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567268-A | Process for preparation of certain tetrahydrofuro[3,4-b]pyridines | MERCK & CO., INC. (US) | 1986-01-28 | — | — | US | disclosed |