Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | CD69 | Q07108 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10829959 | 0.81 | KMT2A (0.37) | CD69KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL10829680 | 0.78 | ALDH1A1 (0.37) | KMT2AKDM4EALDH1A1PTGDR2PKM | |
| SCHEMBL10830004 | 0.78 | PTGDR2 (0.35) | CD69FFAR1KMT2AMAPTKDM4E | |
| SCHEMBL10829782 | 0.76 | CD69 (0.36) | HCAR2CD69KMT2AMAPTKDM4E | |
| SCHEMBL10830680 | 0.76 | HCAR2 (0.39) | HCAR2KMT2AKDM4EPKMHTT | |
| SCHEMBL10830719 | 0.71 | FFAR1 (0.33) | FFAR1PPARG | |
| SCHEMBL10829772 | 0.66 | MAPT (0.35) | KMT2AMAPT | |
| SCHEMBL10829981 | 0.65 | MAPT (0.39) | CD69KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2059331 | 0.65 | KMT2A (0.46) | CD69ELANEKMT2AKDM4EPKM | |
| SCHEMBL10830403 | 0.64 | KMT2A (0.42) | CD69KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4569938-A | Diuretic, antihypertensive and antihistaminic 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1986-02-11 | — | — | US | disclosed |