Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832012 | 0.86 | MAP3K14 (0.41) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL10831348 | 0.86 | AKR1B1 (0.54) | AKR1B1AKR1B10MAPTAKR1A1 | |
| Hydrochloric Acid SCHEMBL10831108 | 0.85 | AKR1B1 (0.53) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL10975805 | 0.73 | AKR1B1 (0.40) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL10830905 | 0.72 | AKR1B1 (0.56) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL10921763 | 0.71 | AKR1B1 (0.71) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL10923913 | 0.71 | AKR1B1 (0.71) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL11146543 | 0.70 | AKR1B10 (0.45) | AKR1B1AKR1B10MAPTAKR1A1MAP3K14 | |
| SCHEMBL11355290 | 0.70 | AKR1B10 (0.39) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL18211725 | 0.69 | MAP3K14 (0.50) | AKR1B1MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4587256-A | ANTIDIABETIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1986-05-06 | — | — | US | disclosed |