SCHEMBL1083140

SCHEMBL1083140

O=C(O)CC(C(=O)O)=C(CCCl)CCCl

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.42
FNTB P49356 2/20 0.42
LDHA P00338 1/20 0.36
SRR Q9GZT4 1/20 0.36
TSHR P16473 2/20 0.35
BBOX1 O75936 1/20 0.31
LMNA P02545 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
SUCNR1 Q9BXA5 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29046207 0.81 FNTA (0.42) FNTAFNTBLDHASRRTSHR
SCHEMBL810648 0.78 FNTA (0.54) FNTAFNTBLDHASRRTSHR
SCHEMBL7118726 0.76 HDAC3 (0.48) FNTAFNTBLDHASRRTSHR
SCHEMBL14354021 0.74 FNTA (0.61) FNTAFNTBLDHASRRTSHR
SCHEMBL10882656 0.73 TSHR (0.39) FNTAFNTBTSHRBBOX1LMNA
SCHEMBL10884922 0.73 TSHR (0.39) FNTAFNTBTSHRBBOX1LMNA
SCHEMBL10882662 0.73 TSHR (0.39) FNTAFNTBTSHRBBOX1LMNA
SCHEMBL14354065 0.73 FNTA (0.70) FNTAFNTBLDHASRRTSHR
SCHEMBL675244 0.73 AKR1B1 (0.44) FNTAFNTBTSHR
SCHEMBL29127352 0.73 LDHA (0.57) FNTAFNTBLDHASRRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2275464-B1 Method for producing a polymer NIPPON SODA CO (JP) 2014-04-23 EP disclosed
US-8536280-B2 Star polymer and coupling agent for anionic polymerization TOHO CHEMICAL INDUSTRY CO., LTD. (JP) 2013-09-17 US disclosed
EP-1892255-B1 ACRYLIC ACID POLYMER NIPPON SODA CO (JP) 2012-08-01 EP disclosed
US-8067515-B2 Method of producing an acrylic acid-based polymer NIPPON SODA CO., LTD. (JP) 2011-11-29 US disclosed
US-20110046333-A1 ACRYLIC ACID-BASED POLYMER AND METHOD OF PRODUCING THE SAME NIPPON SODA CO., LTD. (JP) 2011-02-24 US disclosed
EP-2275464-A1 Method for producing a polymer NIPPON SODA CO., LTD. (JP) 2011-01-19 EP disclosed
US-7847045-B2 Acrylic acid-based polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2010-12-07 US disclosed
US-20100056748-A1 Novel star polymer and coupling agent for anionic polymerization TOHO CHEMICAL INDUSTRY CO., LTD. (JP) 2010-03-04 US disclosed
US-20090111961-A1 Acrylic Acid-Based Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-04-30 US disclosed
US-7494759-B2 Positive resist compositions and process for the formation of resist patterns with the same TOKYO OHKA KOGYO CO., LTD. (JP) 2009-02-24 US disclosed
EP-1892255-A1 ACRYLIC ACID POLYMER AND METHOD FOR PRODUCING SAME NIPPON SODA CO., LTD. (JP) 2008-02-27 EP disclosed
US-20070224538-A1 Positive Resist Compositions and Process for the Formation of Resist Patterns With the Same TOKYO OHKA KOGYO CO., LTD. (JP) 2007-09-27 US disclosed
EP-0089877-B1 INTERPOLYMER LATEX, METHOD OF PRODUCING IT AND APPLICATIONS, ESPECIALLY TO PAPER SIZING RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1986-09-17 EP disclosed
EP-0089877-A1 Interpolymer latex, method of producing it and applications, especially to paper sizing RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-09-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056748-A1 Novel star polymer and coupling agent for anionic polymerization MSN, PAM, STARD10 FNTA 3263/4885FNTB 4222/4885LDHA 1640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.