Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SPTLC2 | O15270 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831654 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAMAPTATMALDH1A1 | |
| SCHEMBL10832466 | 0.94 | PDE4D (0.45) | SMN1; SMN2GAAMAPTATMALDH1A1 | |
| SCHEMBL10832468 | 0.94 | PDE4D (0.45) | SMN1; SMN2GAAMAPTATMALDH1A1 | |
| SCHEMBL10832490 | 0.90 | HSD11B1 (0.40) | SMN1; SMN2GAAMAPTATMALDH1A1 | |
| SCHEMBL10832493 | 0.90 | HSD11B1 (0.40) | SMN1; SMN2GAAMAPTATMALDH1A1 | |
| SCHEMBL10832702 | 0.87 | GPR6 (0.42) | SMN1; SMN2GAAMAPTALDH1A1LMNA | |
| SCHEMBL10832169 | 0.84 | GPR6 (0.40) | SMN1; SMN2MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL10832636 | 0.84 | ALDH1A1 (0.46) | GAAALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL10832175 | 0.83 | GPR6 (0.38) | LMNAKDM4EL3MBTL1 | |
| SCHEMBL10833186 | 0.80 | MAPT (0.45) | SMN1; SMN2GAAMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |
| EP-0083729-B1 | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-02-26 | — | — | EP | disclosed |
| EP-0083729-A1 | Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1983-07-20 | — | — | EP | disclosed |