Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SPTLC2 | O15270 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10832493 | 1.00 | HSD11B1 (0.40) | HSD11B1MAPTGAAATMSMN1; SMN2 | |
| SCHEMBL10832468 | 0.92 | PDE4D (0.45) | MAPTGAAATMSMN1; SMN2POLB | |
| SCHEMBL10832466 | 0.92 | PDE4D (0.45) | MAPTGAAATMSMN1; SMN2POLB | |
| SCHEMBL10831654 | 0.90 | SMN1; SMN2 (0.47) | MAPTGAAATMSMN1; SMN2POLB | |
| SCHEMBL10831650 | 0.90 | SMN1; SMN2 (0.47) | MAPTGAAATMSMN1; SMN2POLB | |
| SCHEMBL10832630 | 0.88 | ALDH1A1 (0.46) | GAAPOLBALDH1A1MEN1LMNA | |
| SCHEMBL10832636 | 0.88 | ALDH1A1 (0.46) | GAAPOLBALDH1A1MEN1LMNA | |
| SCHEMBL10832451 | 0.84 | GPR6 (0.45) | MAPTGAASMN1; SMN2POLBHPGD | |
| SCHEMBL10832289 | 0.83 | GPR6 (0.43) | MAPTSMN1; SMN2TDP1ALDH1A1KMT2A | |
| SCHEMBL10832293 | 0.83 | GPR6 (0.43) | MAPTSMN1; SMN2TDP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581460-A | ANALGESICS | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-04-08 | — | — | US | disclosed |
| EP-0083729-B1 | SUBSTITUTED 1-BENZOYL-2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-02-26 | — | — | EP | disclosed |