Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31619040 | 0.84 | MAPT (0.63) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL4200612 | 0.84 | FLT3 (0.52) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL11757340 | 0.82 | FLT3 (0.46) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL289080 | 0.82 | FLT3 (0.50) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL3807363 | 0.82 | KDM4E (0.51) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL8789115 | 0.82 | FLT3 (0.50) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL28346595 | 0.81 | CA12 (0.49) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL14764371 | 0.79 | FLT3 (0.57) | FLT3MAPTRAB9AMEN1KMT2A | |
| SCHEMBL27512860 | 0.79 | FLT3 (0.47) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL6607462 | 0.79 | ALDH1A1 (0.53) | FLT3MAPTCASP3SENP7TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579865-A | ANTIISCHEMIC, HYPOGLYCEMIC AGENTS | USV PHARMACEUTICAL CORP. (US) | 1986-04-01 | — | — | US | disclosed |
| US-4345932-A | BENZOFURANYL ESTERS | FISONS LIMITED (GB) | 1982-08-24 | — | — | US | disclosed |
| EP-0001486-B1 | PROCESS FOR PREPARING 2,3-DIHYDRO-2,2-DIMETHYL-7-BENZOFURANOL AND BENZODIOXOLE INTERMEDIATE THEREFOR | FMC Corporation (US) | 1982-05-05 | — | — | EP | disclosed |
| US-4157255-A | 2-AMINO-BENZOFURAN-2-YL METHANE SULFONATE | FISONS LIMITED (GB) | 1979-06-05 | — | — | US | disclosed |
| EP-0001486-A2 | Process for preparing 2,3-dihydro-2,2-dimethyl-7-benzofuranol and benzodioxole intermediate therefor | FMC Corporation (US) | 1979-04-18 | — | — | EP | disclosed |
| US-4120871-A | HERBICIDES, PLANT GROWTH REGULATORS | FISONS LIMITED (GB) | 1978-10-17 | — | — | US | disclosed |
| US-4118400-A | THERMAL REARRANGEMENT OF 2-ISOPROPYL-1.3-BENZODIOXOLE, ACID CATALYST | FMC CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |
| US-4013774-A | INSECTICIDAL N-THIO-SUBSTITUTED CARBAMATES OF DIHYDROBENZOFURANOLS | CHEVRON RESEARCH COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-4012436-A | PESTICIDES | CHEVRON RESEARCH COMPANY (US) | 1977-03-15 | — | — | US | disclosed |