Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789115 | 0.86 | FLT3 (0.50) | ALDH1A1KDM4EHPGDMAPTCASP3 | |
| SCHEMBL27512860 | 0.83 | FLT3 (0.47) | ALDH1A1KDM4EHPGDMAPTCASP3 | |
| SCHEMBL3807363 | 0.83 | KDM4E (0.51) | ALDH1A1KDM4EHPGDMAPTCASP3 | |
| SCHEMBL4090737 | 0.83 | FLT3 (0.44) | ALDH1A1KDM4EHPGDMAPTCASP3 | |
| SCHEMBL116771 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDMAPTCASP3 | |
| SCHEMBL4200612 | 0.81 | FLT3 (0.52) | ALDH1A1KDM4EHPGDMAPTCASP3 | |
| SCHEMBL11075359 | 0.80 | KDM4E (0.60) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL289508 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EHPGDMAPTCASP3 | |
| SCHEMBL1116527 | 0.80 | FLT3 (0.47) | ALDH1A1KDM4EHPGDMAPTCASP3 | |
| SCHEMBL289080 | 0.79 | FLT3 (0.50) | ALDH1A1KDM4EHPGDMAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1418906-A1 | AMINOALKYL-SUBSTITUTED AROMATIC BICYCLIC COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Aventis Pharma Deutschland GmbH (DE) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003015769-A1 | AMINOALKYL-SUBSTITUTED AROMATIC BICYCLIC COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-02-27 | — | — | WO | disclosed |