SCHEMBL10831761

SCHEMBL10831761

O=c1sc2ccccc2n1CO

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.64
KDM4E B2RXH2 1/20 0.64
PKM P14618 1/20 0.64
HTT P42858 1/20 0.63
TSHR P16473 3/20 0.58
MAPK1 P28482 3/20 0.58
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
ALDH1A1 P00352 2/20 0.55
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
TDP1 Q9NUW8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4614755 0.85 L3MBTL1 (0.69) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL11350777 0.82 L3MBTL1 (0.66) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL4230610 0.82 L3MBTL1 (0.65) L3MBTL1HTTNPC1RAB9ASMN1; SMN2
SCHEMBL4846941 0.81 L3MBTL1 (0.69) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL281839 0.81 L3MBTL1 (0.64) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL513356 0.81 L3MBTL1 (0.64) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL18676096 0.80 L3MBTL1 (0.58) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL10546592 0.80 L3MBTL1 (0.71) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL11349942 0.79 L3MBTL1 (0.66) L3MBTL1KDM4EPKMHTTTSHR
SCHEMBL11348784 0.79 L3MBTL1 (0.60) L3MBTL1KDM4EPKMHTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4578477-A PLANT GROWTH REGULATORS MONSANTO COMPANY (US) 1986-03-25 US disclosed
US-4474965-A PLANT GROWTH AGENTS MONSANTO COMPANY (US) 1984-10-02 US disclosed
US-4371388-A 3-Substituted aminoalkyl-2-benzothiazolinones as plant growth regulants MONSANTO COMPANY (US) 1983-02-01 US disclosed
EP-0002932-B1 THE USE OF N-SUBSTITUTED OXOBENZOTHIAZOLINES AS PLANT GROWTH REGULATORS AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING N-SUBSTITUTED OXOBENZOTHIAZOLINES MONSANTO COMPANY (US) 1982-09-01 EP disclosed
EP-0007162-B1 NOVEL N-SUBSTITUTED 2-OXO-3-BENZOTHIAZOLINE DERIVATIVES, THEIR USE AS LEGUMINOUS PLANT GROWTH REGULANTS, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING SAID DERIVATIVES AS THE ACTIVE INGREDIENTS MONSANTO COMPANY (US) 1982-07-14 EP disclosed
US-4210439-A N-Substituted oxobenzothiazolines and their use as plant growth regulators MONSANTO COMPANY (US) 1980-07-01 US disclosed
EP-0007162-A1 Novel N-substituted 2-oxo-3-benzothiazoline derivatives, their use as leguminous plant growth regulants, and plant growth regulating compositions containing said derivatives as the active ingredients MONSANTO COMPANY (US) 1980-01-23 EP disclosed
US-4171213-A N-substituted oxybenzothiazoline derivatives and their use as plant growth regulants MONSANTO COMPANY (US) 1979-10-16 US disclosed
EP-0002932-A1 The use of N-substituted oxobenzothiazolines as plant growth regulators and plant growth regulating compositions containing N-substituted oxobenzothiazolines MONSANTO COMPANY (US) 1979-07-11 EP disclosed