SCHEMBL513356

SCHEMBL513356

CCn1c(=O)sc2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.64
KDM4E B2RXH2 1/20 0.64
PKM P14618 1/20 0.64
TSHR P16473 4/20 0.58
MAPK1 P28482 4/20 0.58
HTT P42858 1/20 0.58
TP53 P04637 1/20 0.57
GAA P10253 2/20 0.57
NPSR1 Q6W5P4 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
NPC1 O15118 2/20 0.56
ALDH1A1 P00352 2/20 0.56
RAB9A P51151 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
POLB P06746 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4615852 0.85 L3MBTL1 (0.64) L3MBTL1KDM4EPKMTSHRMAPK1
SCHEMBL11350777 0.82 L3MBTL1 (0.66) L3MBTL1KDM4EPKMTSHRMAPK1
SCHEMBL4617266 0.82 CYP3A4 (0.64) L3MBTL1TSHRSMN1; SMN2NPC1RAB9A
SCHEMBL6419192 0.81 CYP3A4 (0.62) L3MBTL1TSHRSMN1; SMN2NPC1RAB9A
SCHEMBL281839 0.81 L3MBTL1 (0.64) L3MBTL1KDM4EPKMTSHRMAPK1
SCHEMBL4846941 0.81 L3MBTL1 (0.69) L3MBTL1KDM4EPKMTSHRMAPK1
SCHEMBL10831761 0.81 L3MBTL1 (0.64) L3MBTL1KDM4EPKMTSHRMAPK1
SCHEMBL18676096 0.80 L3MBTL1 (0.58) L3MBTL1KDM4EPKMTSHRMAPK1
SCHEMBL17293985 0.80 TSHR (0.67) L3MBTL1KDM4EPKMTSHRMAPK1
SCHEMBL4616279 0.80 NPC1 (0.61) L3MBTL1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240180854-A1 USE OF BETA-ADRENERGIC INVERSE AGONISTS FOR SMOKING CESSATION INVION INC (AU) 2024-06-06 US claimed
CN-106390128-B Use of beta-adrenergic inverse agonists for smoking cessation 伊沃恩有限公司 2022-07-08 CN claimed
CN-103073522-A Synthesis method of 2,2' -biazoyl-di (3-ethyl-benzothiazole-6-sulfonic acid) diammonium salt UNIV JIANGXI NORMAL 2013-05-01 CN claimed
US-7429274-B2 Agent and method for the oxidative coloring of keratin fibers WELLA AG (DE) 2008-09-30 US claimed
EP-1601335-B1 MEANS AND METHOD FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES WELLA AG (DE) 2008-03-19 EP claimed
EP-1699427-B1 AGENT AND METHOD FOR OXIDATIVELY DYING KERATIN FIBERS WELLA AG (DE) 2008-02-27 EP claimed
US-7326254-B2 Means and method for the simultaneous bleaching and dyeing of keratin fibres WELLA AG (DE) 2008-02-05 US claimed
EP-1599178-B1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2007-12-19 EP claimed
US-7291183-B2 Agent and method for dyeing keratin fibers WELLA AG (DE) 2007-11-06 US claimed
US-7244278-B2 Agent and method for oxidative coloring of keratin fibers WELLA AG (DE) 2007-07-17 US claimed
US-20070067927-A1 Agent and method for oxidative coloring of keratin fibers HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2007-03-29 US claimed
EP-1599179-B1 AGENT AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2006-10-11 EP claimed
US-20060162096-A1 Means and method for the simultaneous bleaching and dyeing of keratin fibres HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2006-07-27 US claimed
US-20060010616-A1 Agent and method for dyeing keratin fibers Wella GmbH (DE) 2006-01-19 US claimed
WO-1990006372-A1 SUBSTRATES FOR PEROXIDASE ASSAYING MICROPROBE CORPORATION (US) 1990-06-14 WO claimed
US-RE32769-E LEGUMINOUS PLANT GROWTH REGULATORS MONSANTO COMPANY (US) 1988-10-18 US claimed
CN-222871096-U Automatic cover rebound structure of medicine dispensing device 苏州新劢德医疗器械科技有限公司 2025-05-16 CN disclosed
CN-119929334-A Automatic rebound structure of lid and medicine dispensing device 苏州新劢德医疗器械科技有限公司 2025-05-06 CN disclosed
WO-1990006372-A1 SUBSTRATES FOR PEROXIDASE ASSAYING MICROPROBE CORPORATION (US) 1990-06-14 WO disclosed
US-4430420-A USING AN AMINOSULFONYLHYDRAZONE REDUCING AGENT EASTMAN KODAK COMPANY (US) 1984-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060162096-A1 Means and method for the simultaneous bleaching and dyeing of keratin fibres KRT18, GPX4, NOX4 L3MBTL1 4866/4885KDM4E 1120/4885PKM 43/4885
US-20070067927-A1 Agent and method for oxidative coloring of keratin fibers KRT18, KIT, AOC1 L3MBTL1 4883/4885KDM4E 1510/4885PKM 80/4885
US-20240180854-A1 USE OF BETA-ADRENERGIC INVERSE AGONISTS FOR SMOKING CESSATION ADRB1, ADRB2, ADRB3 L3MBTL1 3626/4885KDM4E 3528/4885PKM 4176/4885
US-20060010616-A1 Agent and method for dyeing keratin fibers KRT18, KIT, MKI67 L3MBTL1 4881/4885KDM4E 1565/4885PKM 156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.