Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2149244 | 0.85 | L3MBTL1 (0.65) | L3MBTL1KDM4EPKMMAPK1TSHR | |
| SCHEMBL11350777 | 0.82 | L3MBTL1 (0.66) | L3MBTL1KDM4EPKMMAPK1TSHR | |
| SCHEMBL318427 | 0.82 | L3MBTL1 (0.68) | L3MBTL1KDM4EPKMMAPK1TSHR | |
| SCHEMBL2149688 | 0.82 | L3MBTL1 (0.56) | L3MBTL1KDM4EPKMMAPK1TSHR | |
| SCHEMBL4095265 | 0.82 | L3MBTL1 (0.56) | L3MBTL1KDM4EPKMMAPK1TSHR | |
| SCHEMBL2148992 | 0.81 | CYP3A4 (0.67) | L3MBTL1RAB9ASMN1; SMN2TDP1NPC1 | |
| SCHEMBL513356 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KDM4EPKMMAPK1TSHR | |
| SCHEMBL10831761 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KDM4EPKMMAPK1TSHR | |
| SCHEMBL281839 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KDM4EPKMMAPK1TSHR | |
| SCHEMBL2149958 | 0.80 | NPC1 (0.65) | L3MBTL1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368434-B2 | Compounds useful for the inhibition of ALDH | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) | 2008-05-06 | — | — | US | disclosed |
| US-20080090972-A1 | Oligomers and Polymers Containing Sulfinate Groups, and Methods for Producing the Same | KERRES JOCHEN | 2008-04-17 | — | — | US | disclosed |
| US-20080090972-A1 | Oligomers and Polymers Containing Sulfinate Groups, and Methods for Producing the Same | KERRES JOCHEN | 2008-04-17 | — | — | US | disclosed |
| US-7288599-B2 | Oligomers and polymers containing sulfinate groups, and method for producing the same | KERRES JOCHEN | 2007-10-30 | — | — | US | disclosed |
| US-7288599-B2 | Oligomers and polymers containing sulfinate groups, and method for producing the same | KERRES JOCHEN | 2007-10-30 | — | — | US | disclosed |
| US-20040068003-A1 | Compounds useful for the inhibition of ALDH | THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC, | 2004-04-08 | — | — | US | disclosed |
| US-4731451-A | HERBICIDES | MONSANTO COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| US-4578477-A | PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1986-03-25 | — | — | US | disclosed |
| US-4427436-A | PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1984-01-24 | — | — | US | disclosed |
| EP-0007161-B1 | NOVEL N-SUBSTITUTED 2-OXO-3-BENZOTHIAZOLINE DERIVATIVES, THEIR USE AS LEGUMINOUS PLANT GROWTH REGULANTS, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING SAID DERIVATIVES AS THE ACTIVE INGREDIENTS | MONSANTO COMPANY (US) | 1981-10-21 | — | — | EP | disclosed |
| US-4258196-A | REACTING THE ANION OF A PRIMARY OR SECONDARY 2-HALOACETAMIDE WITH AN ALKYLATING AGENT | MONSANTO COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4227915-A | N-Substituted oxobenzothiazoline and oxobenzoxazoline derivatives and their use as plant growth regulants | MONSANTO COMPANY (US) | 1980-10-14 | — | — | US | disclosed |
| EP-0007161-A1 | Novel N-substituted 2-oxo-3-benzothiazoline derivatives, their use as leguminous plant growth regulants, and plant growth regulating compositions containing said derivatives as the active ingredients | MONSANTO COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068003-A1 | Compounds useful for the inhibition of ALDH | ALDH2, ALDH1A1, ALDH3A1 | L3MBTL1 3567/4885KDM4E 1630/4885PKM 2128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.